2021 IEEE International Conference on Acoustics, Speech and Signal Processing

6-11 June 2021 • Toronto, Ontario, Canada

Extracting Knowledge from Information

2021 IEEE International Conference on Acoustics, Speech and Signal Processing

6-11 June 2021 • Toronto, Ontario, Canada

Extracting Knowledge from Information

Technical Program

Paper Detail

Paper IDBIO-9.4
Paper Title Unsupervised Multimodal Image Registration with Adaptative Gradient Guidance
Authors Zhe Xu, Jiangpeng Yan, Tsinghua University, China; Jie Luo, Harvard Medical School, United States; Xiu Li, Tsinghua University, United States; Jagadeesan Jayender, Harvard Medical School, United States
SessionBIO-9: Medical Image Analysis
LocationGather.Town
Session Time:Wednesday, 09 June, 14:00 - 14:45
Presentation Time:Wednesday, 09 June, 14:00 - 14:45
Presentation Poster
Topic Biomedical Imaging and Signal Processing: [BIO-MIA] Medical image analysis
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Abstract Multimodal image registration is a fundamental procedure in many image-guided therapies. Recently, unsupervised learning-based methods have demonstrated promising performance over accuracy and efficiency in deformable image registration. However, the estimated deformation fields of the existing methods fully rely on the to-be-registered image pair. It is difficult for the networks to be aware of the mismatched boundaries, resulting in unsatisfactory organ boundary alignment. In this paper, we propose a novel multimodal registration framework, which leverages the deformation fields estimated from both: (i) the original to-be-registered image pair, (ii) their corresponding gradient intensity maps, and adaptively fuses them with the proposed gated fusion module. With the help of auxiliary gradient-space guidance, the network can concentrate more on the spatial relationship of the organ boundary. Experimental results on two clinically acquired CT-MRI datasets demonstrate the effectiveness of our proposed approach.